Providing information for patients and professionals on research and clinical care in genetic types of diabetes.

Latent Autoimmune Diabetes Of Adulthood (LADA)

LADA stands for Latent Auto-immune Diabetes of Adulthood. It is a form of Type 1 diabetes that is diagnosed later and progresses more slowly than childhood Type 1 diabetes. 60% of Type 2 Diabetes present after the age of 20, but the slow onset of LADA makes it hard to differentiate from Type 2 Diabetes. The hallmark of LADA is an autoimmune process characterised by the presence of pancreatic autoantibodies, of which the most useful and robust are glutamic acid decarboxylase antibodies. LADA patients frequently reuire insulin treatment early in their clinical course, but do not completely stop producing a small amount of their own insulin years after diagnosis. They are younger and thinner than Type 2 diabetic patients, without evidence of autoimmunity, and usually insulin deficient rather than insulin resistant.